Palverafusp alfa, CAS [[2850355-87-0]]
Catalog Number:
MCE-HY-P990961
| Article Name: |
Palverafusp alfa, CAS [[2850355-87-0]] |
| Biozol Catalog Number: |
MCE-HY-P990961 |
| Supplier Catalog Number: |
HY-P990961 |
| Alternative Catalog Number: |
MCE-HY-P990961-10MG,MCE-HY-P990961-5MG,MCE-HY-P990961-1MG |
| Manufacturer: |
MedchemExpress |
| Category: |
Antikörper |
| Alternative Names: |
IMM-2510, SYN-2510 |
| Palverafusp alfa (IMM-2510, SYN-2510) is a PD-L1/VEGF-targeting IgG1kappa type humanized antibody. Palverafusp alfa blocks PD-1/PD-L1 binding, relieves immune suppression, mediates PD-L1-directed antibody-dependent cellular cytotoxicity (ADCC). Palverafusp alfa blocks VEGF/VEGFR binding, inhibits angiogenic signaling, relieves VEGF-induced immune suppression. Palverafusp alfa reduces endothelial cell proliferation, enhances ADCC and antibody-dependent cellular phagocytosis (ADCP), inhibits tumor growth, reverses T cell immune suppression. Palverafusp alfa exhibits immune stimulatory, antiangiogenic, and anti-tumor activity in the tumor microenvironment. Palverafusp alfa can be used for the research of cancer, such as solid tumors, non-small cell lung cancer[1]. |
| Molecular Weight: |
(169.11 kDa) |
| Purity: |
98.00 |
| CAS Number: |
[2850355-87-0] |
| Target: |
PD-1/PD-L1,VEGFR |
| Application Notes: |
MCE Product type: Inhibitory Antibodies |
