Clesitamig (ALPS-12) is a trispecific T cell engager with two CD3/CD137 dual-specific Fabs and one DLL3 Fab. Clesitamig engages CD3 and CD137 on T cells to activate and co-stimulate T cells, promoting their proliferation, survival, and antitumor activity. Clesitamig binds to DLL3 on tumor cells for tumor-specific recognition. Clesitamig can be used for the research of small cell lung cancer (SCLC)[1][2].
Molecular Weight:
(195.836 kDa)
Purity:
99.78
CAS Number:
[2930861-48-4]
Target:
CD3
Application Notes:
MCE Product type: Inhibitory Antibodies
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