Ordastobart (INBRX-106, ES-102) is a hexavalent OX40 agonist antibody. Ordastobart enhances OX40 receptor clustering, signaling, and downstream activation, thereby increasing the proliferation and activation of CD4+ and CD8+ T cells in vitro and in vivo. Ordastobart exhibits anti-tumor effects and improves survival in mouse models of cancer. Ordastobart is indicated for research in cancers such as fibrosarcoma and colorectal cancer[1].
Molecular Weight:
(128.96 kDa)
Purity:
98
CAS Number:
[2708115-83-5]
Target:
Orexin Receptor (OX Receptor)
Application Notes:
MCE Product type: Inhibitory Antibodies
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