Sym-021 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. Sym-021 blocks the binding of PD-L1 and PD-L2 ligands, inducing the secretion of interferon IFN-gamma and IL-2 and the proliferation of T cells. Sym-021 has anti-tumor activity in PDX mouse models[1].
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Inhibitory Antibodies
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