SAR-439459 is a human monoclonal antibody (mAb) targeting TGFB1/TGFbeta-1. SAR-439459 blocks TGFbeta-mediated pSMAD signaling, and suppression of T cells and NK cells. SAR-439459 has anti-tumor activity [1].
Target:
TGF-beta Receptor
Application Notes:
MCE Product type: Inhibitory Antibodies
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