Muromonab (Muromonab-CD3, OKT3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients[1][2][3][4][5].
Molecular Weight:
(146.34 kDa)
Purity:
98.74
CAS Number:
[140608-64-6]
Target:
CD3,IFNAR,Interleukin Related
Application Notes:
MCE Product type: Inhibitory Antibodies
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