Zaptuzumab, CAS [[2378046-35-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-P991570
Supplier Catalog Number:
HY-P991570
Alternative Catalog Number:
MCE-HY-P991570-1UNIT
Manufacturer:
MedchemExpress
Category:
Antikörper
Alternative Names:
AD5-10
Zaptuzumab (AD5-10) is a DR5-specific humanized monoclonal antibody that selectively binds to DR5 with high affinity. Zaptuzumab specifically induces cancer cell death by both caspase-apoptosis and autophagic cell death (ACD). Zaptuzumab activates both ADCC and CDC. Zaptuzumab induces ROS generation and GSH level reduction. Zaptuzumab shows a significant suppression of the tumor growth and good safety in various xenografts mice tumor models[1][2][3][4][5].