HB-0017 is a humanized IgG1kappa monoclonal antibody inhibitor, targeting IL-17A. HB-0017 inhibits the IL-6 secretion induced by IL-17A with an IC50 of 2.09 nM. HB-0017 significantly decreases ear thickness in Imiquimod (HY-B0180)-induced psoriasis-like mice model and alleviates inflammations in IL-17A-induced arthritis and air pouch mice model. The isotype control for the HB-0017 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001)[1].
CAS Number:
[2790610-50-1]
Target:
Interleukin Related
Application Notes:
MCE Product type: Inhibitory Antibodies
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