Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia[1].
Molecular Weight:
(144.5 kDa)
Purity:
99.24
CAS Number:
[1446419-85-7]
Target:
ANGPTL
Application Notes:
MCE Product type: Inhibitory Antibodies
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