SIBP-03 is a specifical anti-HER3 antibody. SIBP-03 binds strongly and specifically to recombinant human HER3 protein. SIBP-03 inhibits HER3 activation, as well as the downstream PI3K/AKT signaling pathway. SIBP-03 exhibits anticancer activity against squamous cell carcinoma, non-small cell lung cancer, gastric cancer, and breast cancer. SIBP-03 synergistically enhances the antitumor activity of DS-8201 (HY-138298A) and Cetuximab (HY-P9905)[1][2].
Target:
Akt,EGFR,PI3K
Application Notes:
MCE Product type: Inhibitory Antibodies
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