Efadirelaxin alfa, CAS [[3061442-66-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-P992108
Supplier Catalog Number:
HY-P992108
Alternative Catalog Number:
MCE-HY-P992108-1UNIT
Manufacturer:
MedchemExpress
Category:
Antikörper
Alternative Names:
RELAX10
Efadirelaxin alfa (RELAX10) is a highly selective agonist of relaxin/insulin-like family peptide receptor RXFP1. After subcutaneous administration in animal experiments, Efadirelaxin alfa exhibits a significantly prolonged terminal half-life (7 days in mice, 3.75 days in rats), and shows no activity against related receptors such as RXFP2 and RXFP3. Efadirelaxin alfa has significant anti-cardiac hypertrophy and anti-fibrotic effects. Efadirelaxin alfa effectively attenuates and reverses cardiac hypertrophy and collagen deposition by regulating the TGF-beta1/Smad2 and AKT/eNOS signaling pathways. Efadirelaxin alfa improves cardiac systolic function without causing fluctuations in blood pressure or heart rate, demonstrating favorable safety. Efadirelaxin alfa is currently mainly used in studies related to heart failure[1].
CAS Number:
[3061442-66-5]
Target:
Akt,NO Synthase,RXFP Receptor,VEGFR
Application Notes:
MCE Product type: Inhibitory Antibodies
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