Human Anti-ERBB3 Recombinant Antibody, AMG-888, U3-1287
Patritumab (Human Anti-ERBB3 Recombinant Antibody) is a neutralizing monoclonal antibody to ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors[1].
Molecular Weight:
(146.86 kDa)
Purity:
99.28
CAS Number:
[1262787-83-6]
Target:
Akt,EGFR,ERK,PARP,Survivin
Application Notes:
MCE Product type: Inhibitory Antibodies
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