Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research[1].
Molecular Weight:
(144.8 kDa)
Purity:
99.34
CAS Number:
[1350289-85-8]
Target:
Interleukin Related
Application Notes:
MCE Product type: Inhibitory Antibodies
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