Dinutuximab (APN-311) is a chimeric human-mouse anti-GD2 monoclonal antibody. Dinutuximab can bind to GD2 on the cell surface, triggering antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity, and promoting tumor regression. Dinutuximab can inhibit the growth, invasion, and migration and induce apoptosis of tumor cells. Dinutuximab can be used in the research of tumors such as neuroblastoma and breast cancer[1][2][3].
Molecular Weight:
(145.012 kDa)
Purity:
99
CAS Number:
[1363687-32-4]
Target:
Apoptosis,mTOR,PERK
Application Notes:
MCE Product type: Inhibitory Antibodies
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