Loncastuximab tesirine is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). The antibody portion is Loncastuximab (HY-P99711), and the drug-linker conjugate for ADC is Tesirine (HY-128952). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse large B-cell lymphoma[1][2].
Molecular Weight:
147000 (average)
Purity:
99.37
CAS Number:
[1879918-31-6]
Target:
Antibody-Drug Conjugates (ADCs),Apoptosis
Application Notes:
MCE Product type: ADC Related
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