Spesolimab (BI 655130) is a mouse-derived humanized IgG1k antibody against IL-36R. IL-36 plays an important role in the immune system and Spesolimab is being investigated in palmoplantar pustulosis (PPP). Spesolimab was associated with a reduction in biomarkers associated with the innate, Th1/Th17 and neutrophil pathways[1][2][3][4].
Molecular Weight:
(145.5 kDa)
Purity:
99.10
CAS Number:
[2097104-58-8]
Target:
Interleukin Related
Application Notes:
MCE Product type: Inhibitory Antibodies
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