Prezalumab (AMG 557) is a humanized IgG2 monoclonal antibody targeting ICOSL. Prezalumab inhibits T cell activation and related immune responses by binding to ICOSL and blocking the interaction between ICOS and ICOSL. Prezalumab can be used in the research of autoimmune diseases and inflammatory diseases such as systemic lupus erythematosus. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002)[1][2].
Molecular Weight:
(145.5 kDa)
Purity:
99.23
CAS Number:
[1523164-68-2]
Target:
Interleukin Related,Transmembrane Glycoprotein
Application Notes:
MCE Product type: Inhibitory Antibodies
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