Aselizumab (HuDreg-55) is an humanized IgG4 mAb against L-selectin. However, L-selectin (CD62L) is a cell adhesion molecule expressed on circulating neutrophils. It regulates migrating cells to chemotaxis towards the site of injury. Aselizumab may be account for a high rate of infections and leucopenia after truma[1][2].
Molecular Weight:
(144.74 kDa)
Purity:
99.76
CAS Number:
[395639-53-9]
Target:
P-selectin
Application Notes:
MCE Product type: Inhibitory Antibodies
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