Ianalumab (VAY-736) is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM)[1].
Molecular Weight:
(146.44 kDa)
Purity:
99.97
CAS Number:
[1929549-92-7]
Target:
TNF Receptor
Application Notes:
MCE Product type: Inhibitory Antibodies
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