Latozinemab (AL001) is a recombinant human anti-Sortilin monoclonal antibody. Latozinemab effectively binds Sortilin with a high affinity and blocks the interaction between progranulin protein (PGRN) and Sortilin receptor. Latozinemab has the potential for progranulin gene (GRN) mutations causative of Frontotemporal dementia (FTD) (FTD-GRN) research[1][2].
Molecular Weight:
(146.28 kDa)
Purity:
96.03
CAS Number:
[2376132-27-1]
Target:
Neurotensin Receptor
Application Notes:
MCE Product type: Inhibitory Antibodies
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