Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor beta superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia[1].
Molecular Weight:
(75.71 kDa)
Purity:
98.92
CAS Number:
[1373715-00-4]
Target:
TGF-beta/Smad
Application Notes:
MCE Product type: Inhibitory Antibodies
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