Milatuzumab (hLL1, MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death[1].
Molecular Weight:
(145.66 kDa)
Purity:
99.39
CAS Number:
[899796-83-9]
Target:
CD74
Application Notes:
MCE Product type: Inhibitory Antibodies
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