TI17 is an inhibitor of the thyroid hormone receptor-interacting protein Trip13 and has anticancer activity. TI17 effectively inhibits multiple myeloma (MM) cell proliferation and induces cell cycle arrest and apoptosis. Trip13 is an AAA-ATPase that mediates double-strand break (DSB) repair, TI17 inhibits Trip13 function and increases DNA damage[1].
Molecular Weight:
374.44
Purity:
97
CAS Number:
[1005178-02-8]
Formula:
C23H22N2O3
Target:
Apoptosis,Thyroid Hormone Receptor
Application Notes:
MCE Product type: Reference compound
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