PRMT5-IN-30 (compound 17) is a potent and selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 0.33 µM and a Kd of 0.987 µM. PRMT5-IN-30 exhibits a broad selectivity against a panel of other methyltransferases. PRMT5-IN-30 inhibits PRMT5 mediated SmD3 methylation[1].
Molecular Weight:
371.41
Purity:
99.17
CAS Number:
[330951-01-4]
Formula:
C18H17N3O4S
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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