Itameline (RU 47213) is a prodrug with oral and long-lasting cholinergic activity. Itameline is a novel tetrahydropyridine-oxime that is cleaved in vivo to form an active metabolite, RU 35963. RU 35963 is a muscarinic receptor agonist that is nonselective with respect to receptor subtypes. Itameline possesses the capacity to reduce memory deficits induced by an impairment of cholinergic transmission in the rat[1].
Molecular Weight:
294.73
CAS Number:
[145071-44-9]
Formula:
C14H15ClN2O3
Target:
Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound1
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