ARS-1323 is a KRAS G12C inhibitor. ARS-1323 specifically binds to the cysteine residue on the mutant K-Ras protein, locks it in the GDP-bound conformation, thereby blocking K-Ras activation and downstream signaling pathways. ARS-1323 can be used to investigate the signal transduction mechanisms and growth characteristics of tumor cells driven by K-Ras G12C[1][2].
Molecular Weight:
430.84
Purity:
99.67
CAS Number:
[1698024-73-5]
Formula:
C21H17ClF2N4O2
Target:
Ras
Application Notes:
MCE Product type: Reference compound
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