3,6-DMAD hydrochloride, an acridine derivative, is a potent IRE1alpha-XBP1s pathway inhibitor. 3,6-DMAD hydrochloride promotes IL-6 secretion via the IRE1alpha-XBP1s pathway. 3,6-DMAD hydrochloride inhibits IRE1alpha oligomerization and endoribonuclease (RNase) activity. 3,6-DMAD hydrochloride can be used for research of cancer[1][2].
Purity:
99.50
Formula:
C22H31N5.xHCl
Target:
IRE1
Application Notes:
MCE Product type: Reference compound1
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