5-Aminolevulinic acid (5-ALA, delta-Aminolevulinic acid, 5-Amino-4-oxopentanoic acid) is an orally active heme precursor. 5-Aminolevulinic acid promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid selectively accumulates protoporphyrin IX in tumor cells, as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid can be applied to the research of septic shock, melanoma, and cancer radiotherapy[1][2][3].
Molecular Weight:
131.13
Purity:
99.92
CAS Number:
[106-60-5]
Formula:
C5H9NO3
Target:
Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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