5-Hydroxyindole is an orally active hydroxylated indole and tryptophan metabolite. 5-Hydroxyindole activates alpha7 nicotinic acetylcholine receptors and acts on intestinal L-type calcium channels. 5-Hydroxyindole slows down the desensitization of 5-HT3 receptor-mediated ion currents in cells. 5-Hydroxyindole causes convulsions and loss of consciousness. 5-Hydroxyindole is used in the study of neuroblastoma, schizophrenia, and diseases related to intestinal motility disorders[1][2][3][4][5][6][7].
Molecular Weight:
133.15
Purity:
99.94
CAS Number:
[1953-54-4]
Formula:
C8H7NO
Target:
Calcium Channel,Endogenous Metabolite,nAChR
Application Notes:
MCE Product type: Natural Products
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