()-Nornicotine is a major metabolite of Nicotine. ()-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing alpha7 and alpha6 subunits. ()-Nornicotine disrupts beta-catenin and ZO-1, and induces F-actin depolymerization. ()-Nornicotine supports self-administration behavior. ()-Nornicotine can be used in the research of atherosclerosis, Alzheimers disease, and schizophrenia[1][2][3][4].
Molecular Weight:
148.20
Purity:
98.84
CAS Number:
[5746-86-1]
Formula:
C9H12N2
Target:
Drug Metabolite,Endogenous Metabolite,nAChR,beta-catenin
Application Notes:
MCE Product type: Reference compound1
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