O6-Benzylguanine, CAS [[19916-73-5]]

Product Overview

• Article Name: O6-Benzylguanine, CAS [[19916-73-5]]
• Biozol Catalog Number: MCE-HY-W002585
• Supplier Catalog Number: HY-W002585
• Alternative Catalog Number: MCE-HY-W002585-100MG,MCE-HY-W002585-5MG,MCE-HY-W002585-10MG,MCE-HY-W002585-50MG,MCE-HY-W002585-10MMX1ML,MCE-HY-W002585-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity[1][2].

Product Properties

• Molecular Weight: 241.25
• Purity: 99.97
• CAS Number: [19916-73-5]
• Formula: C12H11N5O
• Target: Apoptosis,DNA/RNA Synthesis

Application Notes

• Application Notes: Reference compound