3-Methyl-2-nitrophenol is a UDP-glucuronyltransferase (EC 2.4.1.17) acceptor substrate that can be confirmed to undergo glucuronidation catalyzed by the enzyme to form a glucuronide conjugate. 3-Methyl-2-nitrophenol functions as a substrate for conjugation, with glucuronidation forming a glucuronide conjugate that eliminates the parent compounds characteristic yellow color. 3-Methyl-2-nitrophenol has higher lipid solubility that contributes to high glucuronidation conversion rate, and exhibits lower absorbance at 340 nm to act as a less interfering substrate for the NADH-NAD+-linked UDP-glucuronyltransferase assay[1].
Molecular Weight:
153.14
Purity:
99.55
CAS Number:
[4920-77-8]
Formula:
C7H7NO3
Target:
UGT
Application Notes:
MCE Product type: Reference compound
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