2 (5H)-Furanone (gamma-Crotonolactone) is an endogenous metabolite. 2 (5H)-Furanone mimics N-acyl homoserine lactone signals, occupies the binding site of LuxR homologs, and interferes with quorum sensing-mediated gene regulation. 2 (5H)-Furanone inhibits quorum sensing mediated by AHLs with different acyl chain lengths. 2 (5H)-Furanone inhibits biofilm formation of environmental *Aeromonas hydrophila* strains on polystyrene plates. 2 (5H)-Furanone suppresses spike-and-wave discharges in a rat model of generalized absence seizures and exhibits selective activity against absence seizures. 2 (5H)-Furanone can be used in studies related to bacteria infections and generalized absence seizures.[1][2]
Molecular Weight:
84.07
Purity:
99.94
CAS Number:
[497-23-4]
Formula:
C4H4O2
Target:
Bacterial,Endogenous Metabolite
Application Notes:
MCE Product type: Natural Products
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