N-(3-Oxohexanoyl)-L-homoserine lactone, CAS [[143537-62-6]]

Product Overview

• Article Name: N-(3-Oxohexanoyl)-L-homoserine lactone, CAS [[143537-62-6]]
• Biozol Catalog Number: MCE-HY-W008806
• Supplier Catalog Number: HY-W008806
• Alternative Catalog Number: MCE-HY-W008806-25MG,MCE-HY-W008806-10MG,MCE-HY-W008806-100MG,MCE-HY-W008806-50MG,MCE-HY-W008806-5MG,MCE-HY-W008806-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: OHHL, N-(3-Oxohexanoyl)homoserine lactone

Product Description

N-(3-Oxohexanoyl)-L-homoserine lactone (OHHL, N-(3-Oxohexanoyl)homoserine lactone) is a specific agonist of LuxR-type transcription factor CarR with a Kd of 1.8 µM. N-(3-Oxohexanoyl)-L-homoserine lactone activates CarR by inducing protein multimerization, promoting its binding to target DNA sequences in the carR-carA intergenic region, thereby upregulating the transcription of carbapenem biosynthesis genes. N-(3-Oxohexanoyl)-L-homoserine lactone acts as a quorum sensing signal molecule, enabling bacteria to coordinate the production of carbapenem antibiotics in a cell density-dependent manner. N-(3-Oxohexanoyl)-L-homoserine lactone is used to study bacterial quorum sensing mechanisms, especially the secondary metabolism and virulence factor regulatory pathways of Erwinia carotovora and Yersinia enterocolitica[1][2][3].

Product Properties

• Molecular Weight: 213.23
• Purity: 99.93
• CAS Number: [143537-62-6]
• Formula: C10H15NO4
• Target: Bacterial

Application Notes

• Application Notes: MCE Product type: Reference compound