Fmoc-7-amino-heptanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. Fmoc-7-amino-heptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Molecular Weight:
367.44
Purity:
98.88
CAS Number:
[127582-76-7]
Formula:
C22H25NO4
Target:
PROTAC Linkers
Application Notes:
MCE Product type: Reference compound
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