2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue[1][2][3][4][5].
Molecular Weight:
225.09
Purity:
99.86
CAS Number:
[524-95-8]
Formula:
C14H16BNO
Target:
Calcium Channel,CRAC Channel,TRP Channel
Application Notes:
MCE Product type: Reference compound
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