Methylisothiazolinone hydrochloride is a bacterial and fungal inhibitor and preservative, as well as a sensitizer. Methylisothiazolinone hydrochloride can activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce apoptosis and inflammatory response. Methylisothiazolinone hydrochloride can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone hydrochloride can cause mitochondrial damage in the endothelium of rat cerebral blood vessels[1][2][3][4].
Molecular Weight:
151.61
Purity:
99.93
CAS Number:
[26172-54-3]
Formula:
C4H6ClNOS
Target:
Apoptosis,Bacterial,Fungal,MMP
Application Notes:
MCE Product type: Reference compound
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