N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly, CAS [[64967-39-1]]

Product Overview

• Article Name: N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly, CAS [[64967-39-1]]
• Biozol Catalog Number: MCE-HY-W010991
• Supplier Catalog Number: HY-W010991
• Alternative Catalog Number: MCE-HY-W010991-25MG,MCE-HY-W010991-10MG,MCE-HY-W010991-500MG,MCE-HY-W010991-100MG,MCE-HY-W010991-250MG,MCE-HY-W010991-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: FAPGG

Product Description

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a specific substrate of angiotensin converting enzyme (ACE) with a Ki of 2.546*10-4 M. It is used as a chromogenic probe for quantitative detection of ACE activity. N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly can be hydrolyzed by ACE to generate N-[3-(2-furyl)acryloyl]-Phe (FAP) and Gly-Gly, and the ACE inhibitory effect is monitored by photometry. FAPGG competitively binds to the active center of ACE and is a key tool for screening ACE inhibitors such as Captopril (HY-B0368) and Dioscorin. Its reversible mechanism of action supports hypertension research and drug development targeting the renin-angiotensin system[1].

Product Properties

• Molecular Weight: 399.40
• Purity: 99.81
• CAS Number: [64967-39-1]
• Formula: C20H21N3O6
• Target: Angiotensin-converting Enzyme (ACE)

Application Notes

• Application Notes: MCE Product type: Dye Reagents