CKI-7 is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 µM and a Ki of 8.5 µM. CKI-7 is a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 has a much weaker effect on casein kinase II and other protein kinases[1][2][3][4].
Molecular Weight:
358.67
Purity:
98.41
CAS Number:
[1177141-67-1]
Formula:
C11H14Cl3N3O2S
Target:
Casein Kinase,CDK,Ribosomal S6 Kinase (RSK),SGK
Application Notes:
MCE Product type: Reference compound
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