Ciglitazone is a potent and selective PPARgamma agonist (EC50=3 µM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells[1][2][3][4].
Molecular Weight:
333.45
Purity:
99.74
CAS Number:
[74772-77-3]
Formula:
C18H23NO3S
Target:
PPAR
Application Notes:
MCE Product type: Reference compound1
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