Norfluoxetine hydrochloride is an active N-demethylated metabolite of Fluoxetine. Fluoxetine is a selective serotonin (5-HT) reuptake inhibitor that is metabolized to Norfluoxetine hydrochloride by cytochrome P450 (CYP) 2D6, CYP2C19, and CYP3A4. Norfluoxetine hydrochloride inhibits 5-HT uptake and inhibits CaV3.3 T current (IC50 = 5 µM). Norfluoxetine hydrochloride has anticonvulsant activity[1][2][3][4].
Molecular Weight:
331.76
Purity:
99.58
CAS Number:
[57226-68-3]
Formula:
C16H17ClF3NO
Target:
5-HT Receptor,Calcium Channel,Drug Metabolite
Application Notes:
MCE Product type: Reference compound1
* VAT and and shipping costs not included. Errors and price changes excepted