NTPO (Nitrilotris methylenephosphonic acid) is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO are abrogated by base excision repair (BER) but not nucleotide excision repair (NER)[1].
Molecular Weight:
299.05
CAS Number:
[6419-19-8]
Formula:
C3H12NO9P3
Target:
DNA Alkylator/Crosslinker
Application Notes:
MCE Product type: Reference compound
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