2-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2-O-Methyluridine can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which decreases ApoB protein levels in HepG2 and prevents IFN-alpha production in isolated human PBMCs. 2-O-Methyluridine level in serum is decreased in patients with breast cancer[1][2][3].
Molecular Weight:
258.23
Purity:
99.91
CAS Number:
[2140-76-3]
Formula:
C10H14N2O6
Target:
Apolipoprotein,Endogenous Metabolite
Application Notes:
MCE Product type: Natural Products
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