Tartronic acid, a dicarboxylic acid derive, is an inhibitor of the transformation of carbohydrates into fat under fat-deficient diet conditions. Tartronic acid promotes 3T3-L1 adipocyte differentiation by increasing the protein expression of FABP-4, PPARgamma and SREBP-1. Tartronic acid promotes de novo lipogenesis and inhibits CPT-1beta by upregulating acetyl-CoA and malonyl-CoA. Tartronic acid promotes weight gain and induces adipocyte hypertrophy in epididymal white adipose tissue and lipid accumulation in the livers of high-fat diet induced obese mice. Tartronic acid can be used for lipid metabolic disease research[1].
Molecular Weight:
120.06
Purity:
98
CAS Number:
[80-69-3]
Formula:
C3H4O5
Target:
Endogenous Metabolite,FABP,PPAR
Application Notes:
MCE Product type: Reference compound
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