Dibenz[a,h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms[1][2].
Molecular Weight:
278.35
Purity:
98
CAS Number:
[53-70-3]
Formula:
C22H14
Target:
Apoptosis,DNA/RNA Synthesis,MDM-2/p53
Application Notes:
MCE Product type: Reference compound1
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