Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 µM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties[1][2][3].
Molecular Weight:
242.31
Purity:
99.34
CAS Number:
[77-40-7]
Formula:
C16H18O2
Target:
Endogenous Metabolite,Estrogen Receptor/ERR,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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