NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver[1][2].
Molecular Weight:
149.15
Purity:
99.67
CAS Number:
[50700-49-7]
Formula:
C8H7NO2
Target:
Drug Metabolite,Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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