CMIT/MIT is a CMIT and MIT mixture. CMIT and MIT are powerful synthetic biocidal substances. CMIT and MIT are used as preservatives in various cosmetics and industrial products. CMIT and MIT are present in many water-soluble consumer products, such as shampoos, toothpastes. CMIT/MIT (3:1 mixture of CMIT and MIT) produces mitochondrial ROS via inhibiting mitochondrial complex I and II. CMIT/MIT (in 3:1 ratio) induces neurotoxicity through the upregulation of the MAPKs signaling pathways. CMIT/MIT can be used in the research of respiratory diseases and neuroblastoma[1][2][3].
Molecular Weight:
264.75
Purity:
97
CAS Number:
[55965-84-9]
Formula:
C8H9ClN2O2S2
Target:
Bacterial,Mitochondrial Metabolism,p38 MAPK,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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