DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an intermediate in melanin synthesis and a component of true black pigment, and its also a moderately potent GPR35 agonist. DHICA shows an ability to stimulate beta-arrestin translocation signaling with an EC50 value of 23.2 µM in the U2OS cell line. DHICA plays a significant role in promoting and protecting against DNA damage[1][2].
Molecular Weight:
193.16
Purity:
97
CAS Number:
[4790-08-3]
Formula:
C9H7NO4
Target:
Arrestin,Endogenous Metabolite,GPR35
Application Notes:
MCE Product type: Reference compound
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