Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A[1][2]. Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc)[3].
Molecular Weight:
1216.64
Purity:
99.85
CAS Number:
[63775-96-2]
Formula:
C63H113N11O12
Target:
Nuclear Factor of activated T Cells (NFAT)
Application Notes:
Peptides
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